1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]-
N-Succinimidyl 11-(maleimido)undecanoate
CAS: 87981-04-2
Molecular Formula: C19H26N2O6
1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]- - Names and Identifiers
1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]- - Physico-chemical Properties
| Molecular Formula | C19H26N2O6 |
| Molar Mass | 378.42 |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Melting Point | 90.0 to 94.0 °C |
| Boling Point | 520.4±42.0 °C(Predicted) |
| pKa | -2.20±0.20(Predicted) |
| Storage Condition | 2-8°C |
1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]- - Introduction
N-succinimidyl ester of 11-maleimidoundecanoic acid (KMUS) is an important reagent commonly used in biochemical research.
Nature:
-Appearance: White solid
-Molecular formula: C21H33N3O5
-Molecular Weight: 407.50
-Melting point: 60-70°C
-Solubility: KMUS is soluble in organic solvents such as dimethyl sulfoxide and chloroform, but has low solubility in water
Use:
-Construction of biomolecular probes: KMUS can react with sulfhydryl groups on proteins, antigens or other biomolecules to achieve selective labeling or covalent linkage to them, for example, to prepare protein probes with fluorescent or emissive labels.
-Synthesis of fluorescent dyes: KMUS can be used as a precursor of fluorescent dyes to prepare fluorescent labeling agents with specific optical properties by combining with different fluorophores.
Preparation Method:
The synthesis of KMUS is mainly carried out by the condensation reaction of 11-maleimidoundecanoic acid (MUS) and succinimide (NHS). Specific reaction conditions and synthetic routes can be experimented with through literature or reference guides.
Safety Information:
- KMUS has a certain degree of irritation, please wear appropriate protective equipment, such as gloves and glasses, during operation.
-Avoid inhalation or direct skin contact. If you accidentally touch, please rinse immediately with plenty of water.
-reasonable storage, avoid high temperature and humid environment.
Nature:
-Appearance: White solid
-Molecular formula: C21H33N3O5
-Molecular Weight: 407.50
-Melting point: 60-70°C
-Solubility: KMUS is soluble in organic solvents such as dimethyl sulfoxide and chloroform, but has low solubility in water
Use:
-Construction of biomolecular probes: KMUS can react with sulfhydryl groups on proteins, antigens or other biomolecules to achieve selective labeling or covalent linkage to them, for example, to prepare protein probes with fluorescent or emissive labels.
-Synthesis of fluorescent dyes: KMUS can be used as a precursor of fluorescent dyes to prepare fluorescent labeling agents with specific optical properties by combining with different fluorophores.
Preparation Method:
The synthesis of KMUS is mainly carried out by the condensation reaction of 11-maleimidoundecanoic acid (MUS) and succinimide (NHS). Specific reaction conditions and synthetic routes can be experimented with through literature or reference guides.
Safety Information:
- KMUS has a certain degree of irritation, please wear appropriate protective equipment, such as gloves and glasses, during operation.
-Avoid inhalation or direct skin contact. If you accidentally touch, please rinse immediately with plenty of water.
-reasonable storage, avoid high temperature and humid environment.
Last Update：2024-04-10 22:29:15
![1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]-](http://res.chembk.com/assets/images/structure/87981-04-2.gif)
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